This Postdoctoral position is part of the functional genomics core of the highly collaborative Environmental Stress pathway project (ESPP). Based in the laboratory of Professor Jay Keasling, this research focuses on a molecular understanding of stress response of the environmentally relevant sulfate reducing bacterium, Desulfovibrio vulgaris Hildenborough. ESPP is in its second project phase where more environmentally relevant aspects of bacterial physiology are being explored, such as metabolism during syntrophic growth with other microorganisms, growth in mixed cultures, exposure of multiple stresses, adaptation, growth conditions and alternate physiological states such as biofilms. This Postdoctoral candidate will work as part of a team to develop computational methods that integrate metabolomics and peptide based mass spectrometric data for measuring metabolic flux distributions in defined syntrophic and mixed cultures. These methods will finally be applied to microbial communities.

Job Duties:

Develop algorithms and write code for extending current flux measurement and prediction techniques to full microbial communities.

Interact extensively with microbiologist for new experimental design, type of samples to be collected, optimization of sample analysis and data collection.

Prepare research results for publication and for presentations at scientific and internal meetings.

Assist in preparation of grant proposals.

Qualifications:

PhD in systems biology, bioinformatics, applied mathematics, theoretical physics or closely related discipline.

Significant experience in Matlab and C, C++ or fortran programming.

Strong interest in microbiology, bacterial metabolism and microbial ecology.

Strong written communication skills.

A commitment to and demonstrated ability to perform collaborative research in an interdisciplinary team environment.

Knowledge of GC and LC MS based mass spectrometry methods for sample analysis.

Knowledge of factors effecting metabolic sample prep.

Knowledge of microbiology, bacterial metabolism, and microbial ecology.

Experience in metabolic flux analysis.

To apply: This is a full-time one-year Term appointment, renewable under the same conditions, contingent upon the continued availability of funding and work. For consideration apply online at: http://jobs.lbl.gov, select "Search Jobs", and enter jobnumber 22250 in the keyword search field.













This is a one year Term appointment, renewable under the same conditions, contingent upon the continued availability of funding and work. For immediate consideration please apply at: http://jobs.lbl.gov/LBNLCareers/details.asp?jid=21615&p=1.















Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce. For more information about LBNL and its programs, visit www.lbl.gov. Information about JBEI can be found at http://jbei.org.