With general guidance, responsible for designing and processing R&D services and preliminary scale-up services for drug discovery projects in order to advance those programs into preclinical development.

This is a great position for a new grad PhD with experience in Organic Synthetic Chemistry.  We are looking for a PhD with under 2 years of industry experience or right out of school!

Responsibilities:

Independently designs, plan and execute experiments for assessing and improving synthetic routes to APIs in support of projects that are in preclinical development through early clinical development

• Perform thorough process research, creative route scouting with the goal of route selection within aggressive timelines
• Independently solve synthetic problems of a moderate scope towards the goal of chemical process development
• Prepare gram to kilogram quantities of APIs, intermediates, impurities, reference standards, and support such activities at CROs
• Performs scale-up, purification, process optimization, technology transfer and process validation activities
• Prepares tech transfer packages allowing larger scale preparation of cGMP-grade material by CMO's
• Performs route development and optimization, standard preparations, and impurity elucidations 
• Prepare technology transfer documents and provide/present project updates
• Develops novel and efficient process chemistry strategies and coordinates research strategies and activities with team members
• Acquires a current understanding of process chemistry literature and methodology, as well as the scientific literature related to the specific drug discovery project
• Keeps an accurate, comprehensible, concise notebook in accordance with company policy
• Influences the course of projects
• With general guidance, learns standards and levels of expectations for routine work; designs experimental strategies
• Learns company‘s discovery process
• Identifies routine obstacles to progress; solves a variety of problems
• May mentor Research Associates
• Supports at least one project of defined scope and moderate complexity
• Represent own research to senior leadership, or for scientific collaborations, or a national scientific conference

Requirements:

• Ph.D. in Chemistry with thesis, publication(s) OR
• MS in Chemistry with minimum 7 years of relevant experience and distinguished publication record, OR
• BS in Chemistry with minimum 12 years of relevant experience and distinguished publication record
• A solid understanding of synthetic organic chemistry
• A high level of proficiency carrying out multi-step syntheses
• Working knowledge of modern synthetic methods, spectroscopy, analytical techniques, and scale-up equipment
• Thorough experience in handling, synthesis, purification, and characterization of complex organic molecules using the latest techniques
• Experience with route scouting as well as route optimization preferred
• Familiarity with project management tools
• Has demonstrated independent thought/creativity in science 
• Ability to convey ideas in an experimentally detailed yet scientifically concise manner
• Excellent communication and multitasking skills
• Expert knowledge of applicable lab equipment
• Possesses a high degree of scientific discretion/intuition

To apply: To apply, em-ail your CV/resume to Meredith Dow:  mdow@proveninc.com or fax to:  (858) 412-1100.  For more information -please call:  858-412-1116.

PROVEN is an employee owned Consulting, Staffing and Solutions firm based in San Diego, CA. Our customer centric approach focuses on the needs of our clients and candidates. We provide flexible consulting and contingent staffing solutions in the areas of Information Technology, Engineering, Finance, Accounting, Scientific and Bio-Technology on a direct-hire, contract-to-hire, and contract basis.

With an average of more than 10 years of Consulting and Staffing experience in addition to specific industry expertise, our team has the knowledge and background to understand your requirements. Our team includes former network professionals, systems analysts, Big 4 Consultants and Scientists.

Our client companies range from start-ups to Fortune 500 in the industries of Pharmaceutical / Biotech, Financial Services, Retail, Manufacturing, Technology, and Government.

PROVEN's Scientific team specializes in identifying the best talent with pre-clinical and clinical experience to service a variety of industries including Biotechnology, Pharmaceutical, Medical Device, Environmental, Chemical, Food & Beverage, Nutraceutical and Cosmetic/Personal Care. Each Partner has a scientific background, which helps us to better understand the needs of our clients.

• Chemistry - Analytical, Medicinal, Organic Synthetic
• Quality Control and Manufacturing Support
• Regulatory Affairs and Quality Assurance
• Biochemistry
• Molecular and Cellular Biology
• Microbiology
• Engineering - Process, Validation, Chemical, Manufacturing, and Quality Engineers