A postdoctoral position is available which is focused upon prostate cancer metastasis. The major areas of investigations are 1) the origin and properties of metastasis-initiating cells (i.e., cancer stem cells), and 2) the signal transduction pathways contributing to the metastatic phenotype. Using a genetically-defined model of mouse prostate cancer, prostate-specific deletion of the PTEN and P53 genes, we have developed a bioluminescent, orthotopic transplantation model of progression and metastasis in which to interrogate questions of cellular and molecular biology.

Candidates should possess a Ph.D., M.D., or D.V.M. and have a strong background in cancer cell biology and/or stem cell biology and/or pathology.

This position is subject to a background investigation.


The NIH is dedicated to building a diverse community in its training and employment programs.

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The National Cancer Institute coordinates the National Cancer Program, which conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients. Specifically, the Institute:

• Supports and coordinates research projects conducted by universities, hospitals, research foundations, and businesses throughout this country and abroad through research grants and cooperative agreements.
• Conducts research in its own laboratories and clinics.
• Supports education and training in fundamental sciences and clinical disciplines for participation in basic and clinical research programs and treatment programs relating to cancer through career awards, training grants, and fellowships.
• Supports research projects in cancer control.
• Supports a national network of cancer centers.
• Collaborates with voluntary organizations and other national and foreign institutions engaged in cancer research and training activities.
• Encourages and coordinates cancer research by industrial concerns where such concerns evidence a particular capability for programmatic research.
• Collects and disseminates information on cancer.
• Supports construction of laboratories, clinics, and related facilities necessary for cancer research through the award of construction grants.