POSTDOCTORAL POSITION
ION CHANNEL PHYSIOLOGY

A postdoctoral position is available immediately in the Laboratory of Neurobiology, National Institute of Environmental Health Sciences (NIEHS/NIH), in Research Triangle Park, NC, to study the function and regulation of nicotinic ACh receptor (nAChR) channels and their role in synaptic physiology and plasticity in the hippocampus. Current projects in the lab utilize hippocampal brain slices and neuronal cultures, as well as various expression systems, to study the role these channels play in regulating hippocampal neuronal activity, as well as how intracellular signal transduction pathways (i.e., phosphorylation, Ca2+) modulate the physiological properties of these channels. In addition to patch-clamp electrophysiological techniques, we utilize various imaging techniques (e.g., confocal, two-photon, and voltage-sensitive dye imaging), as well as laser-induced local photolysis of caged molecules.

Applicants with electrophysiological experience are essential, and expertise in imaging would be a great asset. Applicants must have less than 5 years of postdoctoral experience, and salaries start at an annual rate of ~ $ 46,800 per year (for those with less than 1 year's experience), with annual increases of $ 1,600 per year. For additional information, contact Dr. Jerrel L. Yakel by phone at (919) 541-1407, or by e-mail at yakel@niehs.nih.gov. For additional information concerning the research projects and publications, visit http://www.niehs.nih.gov/research/atniehs/labs/ln/icp/index.cfm.

The National Institute of Environmental Health Sciences (NIEHS) is located in Research Triangle Park, North Carolina.


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The National Institute of Environmental Health Sciences (NIEHS), located in Research Triangle Park, North Carolina, is one of 27 research institutes and centers that comprise the National Institutes of Health (NIH), U.S. Department of Health and Human Services (DHHS). The mission of the NIEHS is to reduce the burden of human illness and disability by understanding how the environment influences the development and progression of human disease.

The NIEHS traces its roots to 1966, when the U.S. Surgeon General announced the establishment of the Division of Environmental Health Sciences within the NIH. In 1969, the division was elevated to full NIH institute status. Since then, the NIEHS has evolved to its present status as a world leader in environmental health sciences, with an impressive record of important scientific accomplishments and a proud history of institutional achievements and growth under the leadership of former directors Paul Kotin, M.D. (1969–1971), David P. Rall, M.D., Ph.D. (1971–1990), and Kenneth Olden, Ph.D. (1991–2005).

Today, under the guidance of its 2006–2011 Strategic Plan, the NIEHS is expanding and accelerating its contributions to scientific knowledge of human health and the environment, and to the health and well-being of people everywhere.