A post-doctoral position in human/statistical genomics is available to be supervised jointly by Dr. Philip de Jager and Dr. Barbara Stranger, in the Departments of Neurology and Medicine, Brigham & Women's Hospital, and Harvard Medical School.

We are looking for an enthusiastic and energetic individual to join our research effort investigating the functional consequences of human genetic variation in the immune system. Specifically, disease-related genetic variation and genome-wide CNP and SNP data will be analyzed in relationship to immunologic profiles derived from RNA expression as well as cytometric and proteomic data generated from several different cell types. The project is an NIH-funded study focusing on the genetic basis of transcript regulation in differentiated immune cell states in large population cohorts comprising multiple ethnicities. The position provides opportunity for integrated analysis of genetic variation (SNPs and copy number variation) with whole-genome gene expression data from multiple immune cell lineages.

The qualified candidate should be highly motivated, with experience in genomics, bioinformatics, computational biology, human population genetics, or a related field, with experience in statistics. He or she should have experience analyzing high-throughput genomic datasets derived from microarray and/or other high-throughput technologies (e.g., experience with GWAS, eQTL, ChIP-Seq, ChIP-chip, or CNVs) and skills in one programming language (R, Perl, Java, or C/C++). An excellent understanding of genetics is required. Because our work involves multiple collaborators, a good balance between independence and team spirit is essential, and effective communication skills are necessary.

The position offers a stimulating and multi-disciplinary environment and the opportunity to work with researchers at Harvard Medical School, Brigham and Women’s Hospital, and the Program in Medical and Population Genetics of the Broad Institute of MIT and Harvard.

Requirements: Ph.D. in Biology, computational biology, statistics, computer science, or related area.

For more information, see: http://dejager_lab.bwh.harvard.edu/ and http://strangerlab.bwh.harvard.edu/

To apply: Application and inquiries should be submitted by e-mail to Barbara Stranger (bstranger@rics.bwh.harvard.edu) or Phil de Jager (pdejager@rics.bwh.harvard.edu).

Along with your CV, please include a cover letter describing previous research, research interests, and future goals. Please provide contact details for 3 referees.