My laboratory in the Experimental Immunology Branch of the National Cancer Institute has a postdoctoral position available to study the Cell Biology of Antigen Processing and Presentation. Our research program is focused on defining the molecular mechanisms by which dendritic cells or B cells activate CD4 T cells. Current projects include identifying the molecular machinery required for MHC class II transport into/out of antigen processing compartments and the characterization of membrane microdomains important for regulating antigen presentation. Our experimental approaches include biochemical and functional analyses using wild-type and genetically altered mice. We have a highly interactive group studying both T cell activation and intracellular protein transport in immune cells.

For additional details please visit our Web site, http://ccr.cancer.gov/Staff/staff.asp?profileid=5655.

Successful applicants must have less than five years of postdoctoral experience and a strong background in basic immunology and molecular biology.

This position is subject to a background investigation.


The NIH is dedicated to building a diverse community in its training and employment programs.

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The National Cancer Institute coordinates the National Cancer Program, which conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients. Specifically, the Institute:

• Supports and coordinates research projects conducted by universities, hospitals, research foundations, and businesses throughout this country and abroad through research grants and cooperative agreements.
• Conducts research in its own laboratories and clinics.
• Supports education and training in fundamental sciences and clinical disciplines for participation in basic and clinical research programs and treatment programs relating to cancer through career awards, training grants, and fellowships.
• Supports research projects in cancer control.
• Supports a national network of cancer centers.
• Collaborates with voluntary organizations and other national and foreign institutions engaged in cancer research and training activities.
• Encourages and coordinates cancer research by industrial concerns where such concerns evidence a particular capability for programmatic research.
• Collects and disseminates information on cancer.
• Supports construction of laboratories, clinics, and related facilities necessary for cancer research through the award of construction grants.