A postdoctoral position is available to determine the structure of an integral outer membrane transporter by X-ray crystallography (see Nature Structural Biology 6, 56-63, 1999; Journal of Molecular Biology 332, 353-368, 2003; EMBO J. 26, 2594-2604, 2007). The transporters we study are vaccine and drug targets against pathogenic bacteria; the crystal structures will aid vaccine and/or drug development. Expression, purification, and crystallization protocols are established for similar projects. Candidates will ideally have some experience in membrane protein expression, purification, crystallization, and/or structure determination by X-ray crystallography. Good biochemistry skills are essential. We are part of an interactive group of structural biologists sharing common home source X-ray facilities, dedicated access to beamlines at APS, and a common weekly group meeting.

Applicants must have a Ph.D. and less than five years of postdoctoral experience. Please click on the button below, or send CV, including the names and addresses of three references, to:

Susan Buchanan
Laboratory of Molecular Biology
NIDDK
Building 50, Room 4503
50 South Drive
Bethesda, MD 20892-8030
E-mail: skbuchan@helix.nih.gov
Web site: http://www.niddk.nih.gov/intram/faculty.asp?People_ID=1554


The NIH is dedicated to building a diverse community in its training and employment programs.

To apply:

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports research on many of the most serious diseases affecting public health. The institute supports much of the clinical research on the diseases of internal medicine and related subspecialty fields as well as many basic science disciplines.

The Institute's Division of Intramural Research encompasses the broad spectrum of metabolic diseases such as: diabetes, obesity, inborn errors of metabolism, endocrine disorders, mineral metabolism, digestive and liver diseases, nutrition, urology and renal disease, and hematology. Basic research studies include: biochemistry, biophysics, nutrition, pathology, histochemistry, bioorganic chemistry, physical chemistry, chemical and molecular biology, and pharmacology.

NIDDK extramural research is organized into four divisions: Diabetes, Endocrinology and Metabolic Diseases; Digestive Diseases and Nutrition; Kidney, Urologic and Hematologic Diseases; and Extramural Activities.

The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, and career development and training awards. The Institute also supports research and development projects and large-scale clinical trials through contracts.