A postdoctoral fellowship position is available as of August 1, 2009, for both U.S. and non-U.S. citizens. The molecular mechanism of steroid receptor action is studied, especially for glucocorticoid, progesterone, and androgen receptors. Projects focus on the ability of novel proteins to cause differential gene expression by modulating receptor transcriptional properties, new targets of these novel proteins and coregulators, selective modifications of gene induction vs. repression, and determinants of agonist vs. antagonist activity. Techniques include chromatin immunoprecipitation and chromatin conformation capture assays with endogenous and exogenous genes, one and two hybrid assays, co-immobilization of proteins, knockout mice, gene knockouts with siRNAs, and the biochemistry of protein-protein interactions.

Applicant should have a strong background in mammalian molecular biology, a Ph.D. or M.D., and less than four years of postdoctoral experience. NIH is an equal opportunity employer.

To apply, click on the button below. For more information, contact:

Steroid Hormones Section/Laboratory of Molecular and Cellular Biology
NIDDK
Building 10, Room 8N307B
8 Center Drive MSC 1772
Bethesda, MD 20892-0805
Phone: (301) 496-6796
Fax: (301) 402-3572
E-mail: steroids@helix.nih.gov


The NIH is dedicated to building a diverse community in its training and employment programs.

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The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports research on many of the most serious diseases affecting public health. The institute supports much of the clinical research on the diseases of internal medicine and related subspecialty fields as well as many basic science disciplines.

The Institute's Division of Intramural Research encompasses the broad spectrum of metabolic diseases such as: diabetes, obesity, inborn errors of metabolism, endocrine disorders, mineral metabolism, digestive and liver diseases, nutrition, urology and renal disease, and hematology. Basic research studies include: biochemistry, biophysics, nutrition, pathology, histochemistry, bioorganic chemistry, physical chemistry, chemical and molecular biology, and pharmacology.

NIDDK extramural research is organized into four divisions: Diabetes, Endocrinology and Metabolic Diseases; Digestive Diseases and Nutrition; Kidney, Urologic and Hematologic Diseases; and Extramural Activities.

The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, and career development and training awards. The Institute also supports research and development projects and large-scale clinical trials through contracts.