The research of this laboratory focuses on: 1) the structure-function of luteinizing (LHR) and prolactin receptors (PRLR) and regulation of their expression by homologous and heterologous hormones. These topics include the regulation of LHR transcription (silencing/derepression: nuclear orphan receptors, epigenetics second messenger), multiple promoter control of PRLR transcription and PRLR forms of relevance to physiological regulation and breast cancer; and 2) regulatory mechanisms involved in the control of steroidogenesis and spermatogenesis (novel gonadotropin-regulated genes, the function of DdX25 and other RNA helicases in spermatogenesis).

Applicants with a background in molecular biology/biochemistry or cell biology must have a Ph.D. and/or M.D. with less than five years of postdoctoral experience. The position is available April 2007.

To apply, click on the button below, or contact:

Endocrinology and Reproduction Research Branch, NICHD
Building 49, Room 6A36
49 Convent Drive MSC 4510
Bethesda, MD 20892-4510
Voice: (301) 496-2021
Fax: (301) 480-8010


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The NICHD was initially established to investigate the broad aspects of human development as a means of understanding developmental disabilities, including mental retardation, and the events that occur during pregnancy. Today, the Institute conducts and supports research on all stages of human development, from preconception to adulthood, to better understand the health of children, adults, families, and communities.