A postdoctoral position is available to study the role of epigenetics in transcriptional regulation by PPARgamma, a master regulator of adipogenesis and a drug target for diabetes. We use a combination of tools, including protein expression and purification, viral vector-mediated gene expression and shRNA knockdown, adipogenesis assay, microarray, chromatin immunoprecipitation, and knockout mice, to study the roles of histone methylation and acetylation in regulation of gene expression and adipogenesis by PPARgamma. Additional information can be found at http://intramural.niddk.nih.gov/research/faculty.asp?People_ID=1637.

Applicants should have a Ph.D. degree with less than 5 years' postdoctoral experience. A strong background in molecular biology is desired. Experience with mouse work or protein purification is a plus.

To apply, click on the button below, or send a cover letter with a brief description of research experience and interests, curriculum vitae, and names of three references to kaig@niddk.nih.gov.


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The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports research on many of the most serious diseases affecting public health. The institute supports much of the clinical research on the diseases of internal medicine and related subspecialty fields as well as many basic science disciplines.

The Institute's Division of Intramural Research encompasses the broad spectrum of metabolic diseases such as: diabetes, obesity, inborn errors of metabolism, endocrine disorders, mineral metabolism, digestive and liver diseases, nutrition, urology and renal disease, and hematology. Basic research studies include: biochemistry, biophysics, nutrition, pathology, histochemistry, bioorganic chemistry, physical chemistry, chemical and molecular biology, and pharmacology.

NIDDK extramural research is organized into four divisions: Diabetes, Endocrinology and Metabolic Diseases; Digestive Diseases and Nutrition; Kidney, Urologic and Hematologic Diseases; and Extramural Activities.

The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, and career development and training awards. The Institute also supports research and development projects and large-scale clinical trials through contracts.