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Cell Biology and Enzymology of Arf GTPase-activating Proteins, Dr. Paul Randazzo
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Employer: National Cancer Institute (NCI)
Location: Bethesda, MD, United States
Posted: July 01, 2008 Expires: January 01, 2009
Job Title: Cell Biology and Enzymology of Arf GTPase-activating Proteins, Dr. Paul Randazzo
Description:

PIs: Drs. Paul Randazzo and Ira Daar - NCI

One postdoctoral position is available immediately in the Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services. The fellow in this position will participate in a multi-disciplined program focused on understanding the function and regulation of Arf GTPase-activating proteins. Several Arf GAPs, including ASAP1, ASAP2, and ARAP2 regulate focal adhesions and control cell migration ASAP1 also associates with invadopodia, stuctures that mediate invasion of cancer cells. Enzymology, biochemistry, and imaging techniques, including confocal and total internal reflection microscopy, will be used to determine molecular mechanisms underlying Arf GAP control of the formation and turnover of these structures.

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This position is subject to a background investigation.


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Employer:

The National Cancer Institute coordinates the National Cancer Program, which conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients. Specifically, the Institute:

  • Supports and coordinates research projects conducted by universities, hospitals, research foundations, and businesses throughout this country and abroad through research grants and cooperative agreements.
  • Conducts research in its own laboratories and clinics.
  • Supports education and training in fundamental sciences and clinical disciplines for participation in basic and clinical research programs and treatment programs relating to cancer through career awards, training grants, and fellowships.
  • Supports research projects in cancer control.
  • Supports a national network of cancer centers.
  • Collaborates with voluntary organizations and other national and foreign institutions engaged in cancer research and training activities.
  • Encourages and coordinates cancer research by industrial concerns where such concerns evidence a particular capability for programmatic research.
  • Collects and disseminates information on cancer.
  • Supports construction of laboratories, clinics, and related facilities necessary for cancer research through the award of construction grants.

Ref Code: PD-4279
Job Type: Postdoctoral researcher
Sector: National lab / Government
Website: http://www.cancer.gov
Hours: Full time
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