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PIs: Drs. Paul Randazzo and Ira Daar - NCI
One postdoctoral position is available immediately in the Laboratory of Cellular and Molecular Biology and the Laboratory of Cellular Developmental Signaling, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services. The fellow in this position will participate in a multi-disciplined program focused on understanding the function and regulation of Arf GTPase-activating proteins in cell adhesion and migration associated with development and cancer cell invasion and metastasis. The project will focus on the ARAP proteins, which are dual Arf GAPs/Rho GAPs that occur only in vertebrates. The ARAPs regulate cell adhesive structures, the actin cytoskeleton, and trafficking of transmembrane receptors. The Xenopus system will be used to determine how the role of ARAPs in cell adhesion and migration affect morphogenetic processes in vivo.
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This position is subject to a background investigation.
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The National Cancer Institute coordinates the National Cancer Program, which conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients. Specifically, the Institute:
- Supports and coordinates research projects conducted by universities, hospitals, research foundations, and businesses throughout this country and abroad through research grants and cooperative agreements.
- Conducts research in its own laboratories and clinics.
- Supports education and training in fundamental sciences and clinical disciplines for participation in basic and clinical research programs and treatment programs relating to cancer through career awards, training grants, and fellowships.
- Supports research projects in cancer control.
- Supports a national network of cancer centers.
- Collaborates with voluntary organizations and other national and foreign institutions engaged in cancer research and training activities.
- Encourages and coordinates cancer research by industrial concerns where such concerns evidence a particular capability for programmatic research.
- Collects and disseminates information on cancer.
- Supports construction of laboratories, clinics, and related facilities necessary for cancer research through the award of construction grants.
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